Agenda Print Version 7:30 – 8:00 a.m. Registration and Continental Breakfast 8:00 – 8:05 a.m. Introduction and Logistics Salvatore Sechi, NIDDK 8:05 – 8:15 a.m. Welcome and Opening Remarks Griffin Rodgers, Director, NIDDK Session I: Novel Methods to Detect Pre-Diabetes and/or Diabetes (Part I) (All presentations should leave 5 minutes for questions and answers) Chair: Salvatore Sechi 8:15 – 8:35 a.m. Screening for Prediabetes abstract Lawrence Phillips, Emory University Biosketch 8:35 – 9:05 a.m. O-GlcNAc: A Potential Diagnostic for Pre-Diabetes abstract Gerald Hart, The Johns Hopkins School of Medicine Biosketch 9:05 – 9:35 a.m. Application of Capillary Liquid Chromatography-Mass Spectrometry Approaches for the Study of Pre-Diabetes and Type 2 Diabetes Mellitus abstract Richard Smith, Pacific Northwest National Laboratory Biosketch 9:35 – 10:05 a.m. Application of N-glycopeptide Analysis Toward a Candidate-based Approach for the Identification of New Markers for Type 2 Diabetes abstract Julian Watts, Institute for Systems Biology Biosketch 10:05 – 10:25 a.m. Coffee Break   Session I: Novel Methods to Detect Pre-Diabetes and/or Diabetes (Part II) (All presentations should leave 5 minutes for questions and answers) Chair: Gerald Hart 10:25 – 10:55 a.m. Analysis of Protein Modifications in Plasma Proteins in Type 2 Diabetes and Prediabetes abstract Daniel Liebler, Vanderbilt University Biosketch 10:55 – 11:25 a.m. Mass Spectrometric Immunoassay in the Discovery of Biomarkers for Type 2 Diabetes abstract Urban Kiernan, Intrinsic Bioprobes Biosketch 11:25 – 11:55 a.m. Markers for T2DM, Risk of T2DM and Aptamer Array Diagnostics abstract Ed Dratz, Montana State University Biosketch 11:55 a.m. – 12:25 p.m. Special Discussion Session Mark Chance, Case Western Reserve University (Chair) Biosketch Cathy Costello, Boston University Biosketch Catherine Fenselau, University of Maryland Biosketch  Marian Rewers, University of Colorado at Denver and Health Sciences Center Biosketch Discussion Questions 12:25 – 1:25 p.m. Lunch (on your own)     Session II: Predictive and Mechanistic Molecular Markers in Diabetes and Its Complications (All presentations should leave 5 minutes for questions and answers) Chair: Gerald Hart 1:25 – 1:55 p.m. Innovative Mass Spectrometry Technology for Diabetes Research abstract Don Hunt, University of Virginia Biosketch 1:55 – 2:25 p.m. Urinary Proteome Analysis Using Capillary Electrophoresis Coupled Mass Spectrometry for the Detection of Diabetes-Associated Pathologies abstract Harald Mischak, Mosaiques Diagnostics & Therapeutics AG Biosketch 2:25 – 2:55 p.m. Mass Spectrometry-Based Approaches for Investigating Protein Disorders abstract Cathy Costello, Boston University School of Medicine 2:55 – 3:15 p.m. Coffee Break     Session III: Examples of Clinical Studies Where Proteomics Might Be Applied (All presentations should leave 5 minutes for questions and answers) Chair: Saul Genuth 3:15 – 3:45 p.m. The DCCT/EDIC Study abstract Saul Genuth, Case Western Reserve University Biosketch 3:45 – 4:15 p.m. Proteomic Opportunities in the Diabetes Prevention Program abstract David Nathan, Harvard Medical School Biosketch 4:15 – 4:45 p.m. United Kingdom Prospective Diabetes Study abstract Rury Holman, University of Oxford Biosketch 4:45 – 5:15 p.m. Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial: Design and Methods abstract Hertzel Gerstein, McMaster University Biosketch 5:15 – 5:45 p.m. The Environmental Determinants of Diabetes in The Young (TEDDY) Study abstract Marian Rewers, University of Colorado 5:45 – 6:05 p.m. Special Discussion Session Santica Marcovina, University of Washington (Chair) Biosketch Nana Gletzu, Emory University Biosketch Ravi Thadhani, Massachusetts General Hospital  Biosketch Discussion Questions 6:05 – 6:15 p.m. Concluding Remarks Judy Fradkin, Director, Division of Diabetes, Endocrinology, and Metabolic Diseases, NIDDK 6:15 p.m. Workshop Adjournment