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Discussion Questions
- What are the sample requirements for proteomic studies?
- Are the samples collected from the above studies suitable for molecular marker discovery and mechanistic studies using proteomic technologies?
- Are there other clinical investigations that could be seen as more appropriate for proteomic analysis intended to identify/characterize markers of diabetes and its complications?
- Do you envision that some of the technologies presented here could be successfully used to analyze samples collected within the clinical studies presented?
- Can any particular technologies presented here be especially well matched with any of the clinical investigations presented here?
- For example, do you think that these technologies are sufficiently mature to address issues such as population stratification in response to treatment in pilot studies?
- If yes, how many samples should be tested in a population stratification pilot study?
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